Gynecology & Obstetrics

Biography

Biography: Muhammad Sultan Islam

Abstract

POLYCYSTIC OVARY SYNDROME (PCOS) An Ovarian dysfunction associated with endocrinopathy in females,is of clinical and public health importance as its very common 0ne out of five women of reproductive age.It has significant and diverse clinical implications including reproductive(infertility,hyperandrogenism,hirsutism),metabolic(insulin resistance,impaired glucose tolerance type 2 diabetes mellitus,adverse cadiovascula risk profiles)and Psychological features(increased anxiety,depression and worsened quality of life).It is a heterogenous condition and involves many things Depending upon on life stage,life style,environmental factors and body weight.it has a unique interactions with ever increasing obesity prevalence worldwide as obesity induced insulin resistance significantly exacerbates all the features of pcos,and risk for metabolic condition reported in first degree relatives.By improving lifestyle aimed at normalizing insulin resistance,improving androgen status and weight management is recognized as a crucial initial treatment strategy but in Pakistan females with lean thin stature also suffered from pcos so the management should focus on support,education,addressing psychological factors and strongly emphasising healthy life style with targeted medical therapy as required with proper care and monitoring.Metabolic complications is also an important part of routine clinical care.comprehensive evidence base guidelines are needed to aid early diagnosis,specific investigations,regular screening and prompt treatment.reproductive features of pcos are well recognized . Treatment.metformin (overweight and obese women),letrozole(only limited data) CC if fails then LOD or Gonadotropins Laproscopic ovarian diathermy(LOD)(To avoid complications such as ovarian hyperstimulation syndrome and multiple pregnancies. Inofolic also plays an important role in reducing weight in obese women but only a limited data .